Search results for "Stereotactic body radiotherapy"

showing 5 items of 5 documents

Stereotactic body radiotherapy in oligoprogressive metastatic castration-resistant prostate cancer during abiraterone or enzalutamide

2022

Introduction: This monocentric, single-arm, retrospective study investigated the role of stereotactic body radiotherapy in patients with metastatic castration resistant prostate cancer who experienced oligoprogression during androgen receptor targeted agents. Methods: We retrospectively enrolled metastatic castration resistant prostate cancer patients treated with androgen receptor targeted agents between December 2016 and January 2022. All patients experienced an oligoprogression (defined as the appearance and/or the progression of ⩽5 bone or nodal or soft tissue metastases) during treatment with androgen receptor targeted agents and received stereotactic body radiotherapy upon oligoprogre…

Cancer ResearchenzalutamideOncologyStereotactic body radiotherapyabirateronemetastatic castration resistant prostate cancerGeneral Medicineoligometastatic diseaseSettore MED/36 - Diagnostica Per Immagini E RadioterapiaTumori Journal
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Early Impact of Pulmonary Fractionated Stereotactic Body Radiotherapy on Quality of Life:Benefit for Patients With Low Initial Scores (STRIPE Trial)

2019

Abstract Introduction Quality of life (QoL) of comorbid patients with pulmonary malignancies is a key issue in considering fractionated stereotactic body radiotherapy (SBRT) indication. This study investigates the early impact of SBRT on QoL. Methods One hundred patients with pulmonary lesions were treated with SBRT from February 2011 to December 2014 within the prospective, monocenter, phase II STRIPE trial. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core module (EORTC QLQ-C30) and the QLQ-LC13 lung cancer-specific questionnaire were used to evaluate QoL before, 2 and 7 weeks after SBRT, then every 3 months for 2 years. We report on the ana…

Male0301 basic medicinePulmonary and Respiratory Medicinemedicine.medical_specialtyLung NeoplasmsHealth StatusRadiosurgeryEmotional function03 medical and health sciences0302 clinical medicineQuality of lifeSurveys and QuestionnairesInternal medicinemedicineHumansProspective StudiesAgedLungbusiness.industryCancerPrognosismedicine.diseasehumanitiesKarnofsky index030104 developmental biologymedicine.anatomical_structureOncology030220 oncology & carcinogenesisCharlson comorbidity indexQuality of LifeFemaleDose Fractionation RadiationbusinessStereotactic body radiotherapyFollow-Up StudiesJournal of Thoracic Oncology
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Available evidence on re-irradiation with stereotactic ablative radiotherapy following high-dose previous thoracic radiotherapy for lung malignancies

2015

Patients affected with intra-thoracic recurrences of primary or secondary lung malignancies after a first course of definitive radiotherapy have limited therapeutic options, and they are often treated with a palliative intent. Re-irradiation with stereotactic ablative radiotherapy (SABR) represents an appealing approach, due to the optimized dose distribution that allows for high-dose delivery with better sparing of organs at risk. This strategy has the goal of long-term control and even cure. Aim of this review is to report and discuss published data on re-irradiation with SABR in terms of efficacy and toxicity. Results indicate that thoracic re-irradiation may offer satisfactory disease c…

ThoraxRe-Irradiationmedicine.medical_specialtyLung NeoplasmsStereotactic body radiotherapymedicine.medical_treatmentLung cancer; Re-irradiation; Stereotactic ablative radiotherapy; Stereotactic body radiotherapy; Thoracic relapseLung cancer; Re-irradiation; Stereotactic ablative radiotherapy; Stereotactic body radiotherapy; Thoracic relapse; Humans; Lung Neoplasms; Patient Selection; Radiotherapy Dosage; Thorax; Radiosurgery; Oncology; Radiology Nuclear Medicine and ImagingSABR volatility modelRadiosurgeryRadiosurgeryNuclear Medicine and ImagingAblative casemedicineHumansRadiology Nuclear Medicine and imagingLung cancerThoracic relapsebusiness.industryPatient SelectionRetrospective cohort studyRadiotherapy DosageGeneral MedicineThoraxmedicine.diseaseRadiation therapyOncologyRe-irradiationRadiologyStereotactic ablative radiotherapyLung cancerbusinessRadiology
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Spinal metastases: Is stereotactic body radiation therapy supported by evidences?

2016

Stereotactic body radiotherapy (SBRT) is becoming widely adopted in the treatment of primary and secondary tumors. Spinal bone metastases are frequently discovered in cancer patients, and in the past have been usually treated with a palliative goal. Nevertheless, in some particular clinical settings, such as oligometastatic patients and/or those with a long life expectancy, spinal SBRT could be considered a valid therapeutic option to obtain long-lasting palliation and, when possible, with a curative goal. This review aims to summarize available clinical and dosimetric data of published studies about spinal SBRT.

medicine.medical_specialtyPalliative careStereotactic body radiation therapymedicine.medical_treatment2720 HematologyBone Neoplasms610 Medicine & healthClinical settingsRadiosurgeryRadiosurgery030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineDosimetryFractures CompressionPalliative radiotherapymedicineHumansSBRTSpinal NeoplasmsToxicitySpine metastasesbusiness.industryPalliative CareCompressionCancerRadiotherapy DosageHematologymedicine.disease10044 Clinic for Radiation OncologySurgeryTreatment OutcomeOncologyLocal controlDosimetry; Local control; Palliative radiotherapy; SBRT; Spine metastases; Toxicity; Bone Neoplasms; Evidence-Based Practice; Fractures Compression; Humans; Palliative Care; Radiotherapy Dosage; Spinal Fractures; Spinal Neoplasms; Treatment Outcome; Radiosurgery; Hematology; Oncology; Geriatrics and GerontologyEvidence-Based Practice030220 oncology & carcinogenesisSpinal Fractures2730 OncologySecondary tumorsGeriatrics and GerontologySpinal metastasesbusinessFracturesStereotactic body radiotherapyCritical Reviews in Oncology/Hematology
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Reimbursement of radiotherapy in Germany.

2017

Reimbursement of radiotherapy in Germany is mainly based on a certain fixed fee for treatment planning and patient set up in addition to payment per fraction. This applies to outpatient care for patients with public health insurance or private health insurance. Payment per fraction has a considerable influence on reimbursement of inpatients as well. The advantage of payment per fraction is the simplicity and transparency. The disadvantage is an inadequate reimbursement for new treatment modalities like hypofractionation or stereotactic body radiotherapy.

medicine.medical_specialtyTransparency (market)media_common.quotation_subjectmedicine.medical_treatmentReimbursement Mechanisms03 medical and health sciences0302 clinical medicineAmbulatory careGermanyMedicineHumansRadiology Nuclear Medicine and imaging030212 general & internal medicineRadiation treatment planningIntensive care medicinehealth care economics and organizationsDisadvantageReimbursementmedia_commonRadiotherapybusiness.industryPaymentRadiation therapyOncology030220 oncology & carcinogenesisbusinessStereotactic body radiotherapyCancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
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